POLYFUNCTIONAL POLYHEMOGLOBIN-ENZYME COMPLEX Russian patent published in 2011 - IPC A61K38/42 A61K38/43 A61P7/00 

Abstract RU 2432172 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to medicine, and concerns oxygen-transport blood substitutes, namely to a polyfunctional polyhemoglobin-enzyme complex consisting of polyhemoglobin molecules of various compositions of molecular mass in the range 300-3300 kDa produced with the use of glutaric aldehyde.

EFFECT: invention provides production of the blood substitute with optimum oxygen-transport properties and functioning time in a circulatory bed without involving kidneys, inducing erythrocyte aggregation, and also causing osmotic vascular pressure failure; the blood substitute exhibit antioxidant, vasodilating and antithrombotic properties.

1 cl, 1 ex

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RU 2 432 172 C1

Authors

Vashanov Gennadij Afanas'Evich

Lavrinenko Igor' Andreevich

Ruban Mikhail Konstantinovich

Dates

2011-10-27Published

2010-02-24Filed