FIELD: medicine.
SUBSTANCE: invention concerns experimental medicine, namely to experimental surgery and is intended for modeling of an autoimmune stomach ulcer at rats. For this purpose double introduction of the water-salt antigen containing an admixture of a homogenate of allogenic mucosa of a stomach in a normal saline solution and full Freund's adjuvant, at a parity of components of an admixture 1:2 is performed to an animal in 1 and 10 days. In addition the water-salt antigen containing an admixture of a homogenate of an allogenic mucosa of a stomach in a normal saline solution and incomplete Freund's adjuvant, at a parity of components of an admixture 1:1 is entered to an animal on the 15 day.
EFFECT: provides adequate reproduction of the model.
2 dwg, 4 cl
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF MODELLING AUTOIMMUNE GASTRITIS IN RATS | 2007 |
|
RU2356102C1 |
| METHOD OF MODULATING POST-TRANSPLANTATION CHANGING IN KIDNEYS | 2014 |
|
RU2557701C1 |
| METHOD FOR SIMUATION OF SEVERE SPONTANEOUSLY IRREVERSIBLE LIVER DAMAGE | 2016 |
|
RU2633296C1 |
| METHOD OF MODELLING TYPE I DIABETES MELLITUS IN RATS | 2009 |
|
RU2400822C1 |
| METHOD FOR MODELING ALCOHOL-INDUCED NEPHROPATHY AGAINST THE BACKGROUND OF AUTOIMMUNE NEPHRITIS IN RATS IN AN EXPERIMENT | 2021 |
|
RU2771258C1 |
| SUBSTANCE ELICITING CAPACITY TO ACTIVATE REGENERATIVE-REPARATIVE PROCESSES IN DIGESTIVE TRACT MUCOSA | 2003 |
|
RU2233166C1 |
| METHOD OF TREATING MUCOSAL LESIONS OF GASTROINTESTINAL TRACT | 2007 |
|
RU2355415C2 |
| METHOD OF MODELLING AUTOIMMUNE OOPHORITIS | 2010 |
|
RU2439712C1 |
| METHOD OF REGULATORY ACTION ON PRIMARY MECHANISMS OF BODY DEFENSE REACTIONS IN NORMAL AND PATHOLOGICAL STATES: IMMUNE REACTION, INFLAMMATORY REACTIONS, AND FREE-RADICAL PROCESS USING GAMMA-GLUTAMYLHISTAMINE | 1999 |
|
RU2180842C2 |
| APPLICATION OF Fc-FRAGMENTS OF IMMUNOGLOBULIN CLASS G AS ANTIGEN FOR TREATING RHEUMATOID ARTHRITIS, REMEDY AND METHOD OF TREATING | 2008 |
|
RU2385164C1 |
