WAY OF RECEPTION OF URANIUM-230 RADIONUCLIDE FOR THERAPY OF ONCOLOGIC DISEASES Russian patent published in 2009 - IPC A61K51/00 A61K103/40 G21G1/10 C22B60/02 

FIELD: medicine.

SUBSTANCE: invention concerns radionuclide reception ²³⁰U for therapy of oncologic diseases. The invention allows simplifying process of manufacture of a radio drug on the basis of short-living α-nuclides due to a natural radionuclide ²³⁰Th. The way includes irradiation of the target containing a natural isotope of thorium - ²³⁰Th in a proton beam of a cyclotron. A target radioactive isotope ²³⁰Th is accumulated in a target in the course of threshold nuclear reaction ²³⁰Th (p, n) ²³⁰Pa→²³⁰U. As a target material bonds of ²³⁰ThF₄ or ²³⁰ThO₂ or metal ²³⁰Th are used. The irradiated target is taken from the accelerator, held and exposed to radiochemical clearing for radioactive isotope reception ²³⁰U of standard quality. The chain of natural disintegration of an isotope ²³⁰U leads to an output of the α-particles used in a nuclear medicine for therapy of oncologic diseases.

EFFECT: simplification of process of manufacture of a radio drug on the basis of short-living α-nuclides due to a natural radionuclide ²³⁰Th.

2 cl, 1 dwg