N,N'-DIFLUORBORYL COMPLEXES OF N-(3-ARYL-2H-ISOINDOL-1-YL)-N-(3-ARYL-1H-ISOINDOL-1-YLIDENE)AMINES AND METHOD OF OBTAINING THEM Russian patent published in 2009 - IPC C07F5/02 A61P35/00 

Abstract RU 2364600 C1

FIELD: chemistry.

SUBSTANCE: invention relates to novel class of photosensibilisers for photodynamic therapy - N,N-difluorboryl complexes of N-(3-aryl-2H-isoindol-1-yl)-N-(3-aryl-1H-isoindol-1-ylidene)amines of general formula: , where R=H,C1-C4-alkyl, OC1-C4-alkyl, Ph, Br, as well as to method of obtaining them lying in processing of respective ligand with boron trifluoride etherate in presence of secondary or tertiary amine in boiling benzole.

EFFECT: described photosensibilisers possess high photoinduced activity and are promising for practical application in photodynamic therapy method.

2 cl, 7 ex, 2 tbl

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RU 2 364 600 C1

Authors

Barkanova Svetlana Vasil'Evna

Vorozhtsov Georgij Nikolaevich

Donjagina Valentina Fedorovna

Ivanova-Radkevich Veronika Igorevna

Luk'Janets Evgenij Antonovich

Umnova Ljubov' Vasil'Evna

Dates

2009-08-20Published

2008-01-14Filed