NOVEL AMPHYL DERIVATIVES OF ALFA-C-PHENYL-N-TRET-BUTYLNITRONE Russian patent published in 2009 - IPC C07H15/18 C07C323/03 A61K31/7016 A61K31/15 A61P39/06 A61Q19/08 C07H3/04 

Abstract RU 2364602 C2

FIELD: chemistry.

SUBSTANCE: claimed invention relates to derivatives of α-C-phenyl-N-Tret-butylnitrone of general formula (I) , where X represents lactobionamide group, quarternary ammonium group or group ; m represents 1, 2 or 3; y represents 0 or 1; Y represents group -CH2-; m' represents 1; X' represents alkyl chain C4-C14, if necessary substituted with one or several fluorine atoms; Y' represents group selected from functional amide group (-NHC(O)-), urethane group (-OC(O)NH-) or thioester bridge (-S-).

EFFECT: invention also relates to application of claimed compounds for obtaining medication for treatment of pathologies induced by oxidative stress and formation of compounds with free oxygen radicals and to application of formula (I) compounds for obtaining cosmetic composition for prevention and treatment of ageing effects.

9 cl, 4 tbl, 11 dwg

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RU 2 364 602 C2

Authors

Djuran Gregori

Polidori Anzh

Puchchi Bernar

Dates

2009-08-20Published

2003-11-07Filed