NOVEL SURFACTANTS AND USE THEREOF Russian patent published in 2010 - IPC C07C323/60 A61K9/127 

Abstract RU 2395493 C2

FIELD: chemistry.

SUBSTANCE: present invention relates to novel surfactants of formula III and their use in obtaining nanoparticles which serve as vectors for biologically active ingredients. , and , where R3 is selected from group IV or V; Y is a sulphur atom or -NH-CO-(CH2)n-X-; X is a sulphur atom or -CH2-; n and y are integers from 0 to 10; R is a hydrocarbon, fluorinated hydrocarbon or thioalkyl; W is -NH- or CH2-; p is an integer from 1 to 50; m is an integer from 0 to 9; and if X = CH2, 0 < m+n < 6; x is an integer from 0 to 30; R1 is selected from the following radicals: where R' is H or polyhydroxylated hydrocarbon; R2 is an identification group which has affinity to a biological target; Z is a spacer group.

EFFECT: design of novel surfactants and nanoparticles based on the said surfactants.

22 cl, 9 ex, 2 tbl, 8 dwg

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RU 2 395 493 C2

Authors

Puchchi Bernar

Polidori Anzh

Mishel' Nikolja

Fab'Jano Ann-Sil'Vi

Kontino-Pepehn Kristin

Sall' Zhan-P'Er

Dates

2010-07-27Published

2004-10-19Filed