2-AMINO-2-PHENYLALKANOL DERIVATIVES, PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Russian patent published in 2013 - IPC C07C219/26 C07C271/22 C07C333/04 A61K31/24 A61K31/27 A61P29/00 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to new 2-amino-2-phenylalkanol derivatives possessing analgesic activity. In formula (I):

R₁ represents a hydrogen atom, alkyl radical containing 1 to 4 carbon atoms in a linear or branched chain, alkyl radical containing 2 to 4 C in a linear or branched chain, substituted hydroxy, alkoxy, alkylthio, acyloxy, amino, alkylamino, dialkylamino, alkylcarbamoyloxy, alkoxycarbonylamino, ureido or alkylureido, R₂ represents -CO-R radical, -CO-Y-R₄ radical, or R₂ represents an alkyl radical containing 2 to 4 C, substituted hydroxy, alkoxy, alkylthio, acyloxy, amino, alkylamino, dialkylamino with alkyl residues thereof forming together with a nitrogen atom whereto attached, a heterocycle having 5 or 6 members, optionally carrying another heteroatom specified in oxygen or nitrogen, or substituted by alkylcarbamoyloxy, alkoxycarbonylamino, ureido or alkylureido. It will be appreciated that the above substituted alkyl radical represents a linear or branched chain, and contains at least 2 carbon atoms between a nitrogen atom carrying R₂ and a substitute; R₃ represents an alkyl radical containing 1 to 4 carbon atoms in a linear or branched chain. The radical values R, R₄, R₅, Y are presented in the patent claim.

EFFECT: what is presented is a method for preparing said compounds and a pharmaceutical composition containing them.

6 cl, 17 ex