DERIVATIVES OF N-(1,5-DIPHELYL-1H-PYRAZOL-3-YL)SULPHONAMIDE WITH AFFINITY TO CB RECEPTORS Russian patent published in 2009 - IPC C07D231/12 C07D409/12 C07D413/14 A61K31/415 A61K31/4155 A61P1/00 A61P25/00 A61P29/00 A61P37/00 

Abstract RU 2366657 C2

FIELD: chemistry.

SUBSTANCE: present invention refers to compounds of general formula (I) in the state of base salt or acid-addition salt, to method of their preparation and to the pharmaceutical composition thereof In the said formula R1 is (C1-C6)alkyl; (C3-C7)cycloalkyl unsubstituted or substituted once or more than once; (C3-C7)cycloalkylmethyl unsubstituted or substituted once or more than once; phenyl unsubstituted or substituted ; benzyl unsubstituted or substituted once or twice ; thienyl unsubstituted or substituted ; R2 is atom hydrogen or (C1-C3)alkyl; R3 is (C1-C5)alkyl; R4, R5, R6, R7, each R8 and R9 independently represents the atom of hydrogen, atom of halogen, (C1-C7)alkyl, (C1-C5)alkoxy or trifluoromethyl radical; n is 0, 1 or 2; Alk is (C1-C4)alkyl.

EFFECT: new compounds possess useful biological activity.

5 cl, 5 tbl, 4 ex

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RU 2 366 657 C2

Authors

Bart Fransis

Konzhi Kristian

Martines Serzh

Rinal'Di-Karmona Mjuriehll'

Dates

2009-09-10Published

2005-01-07Filed