PHARMACEUTICAL COMBINED COMPOSITION FOR LOCAL AND EXTERNAL USE ON BASIS OF DIOXIDINE Russian patent published in 2018 - IPC A61K31/513 A61K31/00 A61K38/43 A61K9/00 A61P17/02 

FIELD: pharmaceuticals.

SUBSTANCE: group of inventions refers to pharmaceutical compositions used in the treatment of extensive purulent-necrotic post-traumatic, postoperative wounds. Compositions for topical or topical application according to the invention contain 0.1–5 % by weight of dioxidine, a hydrophilic base and at least one target additive selected from the group: 0.5–6.5 % by weight anesthetic, 0.05–16 % by weight of a complex of proteolytic enzymes, 0.001–5 % by weight of a synthetic antibacterial agent that reduces the resistance of microorganisms, 0.5–5 % by weight of an antibiotic, 0.05–12.5 % by weight of synthetic immunomodulator, dimexidum, stimulator of reparative processes, antimycotic.

EFFECT: invented combined composition creates optimal conditions for shortening the periods of systemic antimicrobial and antifungal therapy, allows to accelerate the healing process, improve the conditions for wound healing.

19 cl, 43 ex, 1 tbl