METHOD OF PRODUCTION OF POLYELECTROLYTE NANO- AND MICROCAPSULES WITH PROTEIN CONTENT Russian patent published in 2009 - IPC A61K9/51 A61K38/43 

FIELD: medicine.

SUBSTANCE: at first component microspherolites of carbonates of alkaline earth metals and encapsulatable protein are prepared, then capsules are made by sequential adsorption into composite microsperolites of oppositely charged polyelectrolytes to be preselected by sequential examination of each polyelectrolyte effect on encapulatable protein in the solution. The carbonates of alkaline earth metals are removed from capsules by means of EDTA or another chelating agent or by means of acidification. Polyelectrolytes are taken as biodegradable biodegradation deficient complex cations and polyanious of predominantly linear structure. After absorption of required quantity of polyelectrolyte layers the protein activity shall be controlled.

EFFECT: retention of functional properties of protein during its encapsulation.

6 cl, 2 ex, 5 dwg