FIELD: medicine.
SUBSTANCE: invention relates to pyrazol derivatives, represented by general formula: 
, where R1 - R6 take on values, determined in the invention formula; one of Q and T is a group, presented by the general formula: 
or a group, presented by the general formula: 
, whereas the other one represents C1-6 alkyl group, halogen (C1-6 alkyl) group or C3-7 cycloalkyl group; X, Y and Z take on values, determined in the invention formula; to their pharmaceutically acceptable salts that possess inhibitory activity in regard to SGLT1 human being.
EFFECT: possibility of application in pharmaceutical compositions for prevention or treatment of the disease, connected with hyperglycemia.
25 cl, 223 ex, 12 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| PYRAZOLE DERIVATIEVES, MEDICAL COMPOSITIONS, CONTAINING SAID DERIVATIVES, THEIR APPLICATION IN MEDICINE AND INTERMEDIATE COMPOUNDS FOR THEIR OBTAINING | 2003 |
|
RU2356906C2 |
| DERIVATIVES OF GLUCOPYRANOSYLOXYPYRAZOLE AND THEIR USING IN MEDICINAL AGENTS | 2001 |
|
RU2317302C2 |
| GLUCOPYRANOSYLOXYPYRAZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE DERIVATIVES AND INTERMEDIATE COMPOUNDS FOR THEIR PREPARING | 2000 |
|
RU2232767C2 |
| DERIVATIVES OF ARYL-5-THIO-β-D-GLYCOPYRANOSIDE AND THERAPEUTIC AGENT COMPRISING THEREOF USED IN DIABETES MELLITUS | 2003 |
|
RU2322449C2 |
| SPIROKETAL DERIVATIVES AND USE THEREOF AS MEDICINAL AGENT AGAINST DIABETES | 2006 |
|
RU2416617C2 |
| C-PHENYL-1-THIOGLUCITOLS | 2007 |
|
RU2434862C2 |
| 1-THIO-D-GLUCITOL DERIVATIVES | 2006 |
|
RU2387649C2 |
| C-PHENYL GLYCITOL COMPOUND FOR TREATING DIABETES | 2007 |
|
RU2437876C2 |
| NOVEL CYCLOHEXANE DERIVATIVE, PRODRUG AND SALT THEREOF AND DIABETES THERAPEUTIC AGENT CONTAINING SAID COMPOUNDS | 2005 |
|
RU2394015C2 |
| LOCAL ANTIMYCOTIC AGENT | 2012 |
|
RU2593990C2 |
