N-PHENYLPHOSPHORIC ACID TRIAMIDES, METHOD OF OBTAINMENT AND APPLICATION AS REGULATION AND INHIBITION AGENTS FOR ENZYMIC CARBAMIDE HYDROLYSIS Russian patent published in 2009 - IPC C07F9/22 C05G3/08 A61K31/664 A61P1/04 A61P13/04 A61P13/02 

Abstract RU 2370498 C2

FIELD: pharmacology.

SUBSTANCE: invention concerns N-phenylphosphoric acid triamides of general formula (I), method of their obtainment and application as inhibition agents in enzymic hydrolysis of carbamide , where X is oxygen or sulphur; R1, R2, R3, R4 are selected out of hydrogen, C1-C8 alkyl, alcoxy, fluorine, chlorine, bromine, iodine, trifluoromethyl.

EFFECT: obtaining novel efficient urease inhibitors.

12 cl, 4 ex, 1 tbl

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RU 2 370 498 C2

Authors

Khukke Andre

Niklas Khans-Joakhim

Voznjak Khartmut

Mikhel' Khans-Jurgen

Shuster Karola

Dates

2009-10-20Published

2005-02-04Filed