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2 371 200

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(51)

IPC

A61K39/395(2006-01-01)

C07K16/06(2006-01-01)

(21) (22)

Application

2008122064/15, 2008-06-03

(24)

Start date

2008-06-03

(22)

Actual filing date

2008-06-03

(45)

Published

2009-10-27

(72)

Inventor

Melikhova Aleksandra VadimovnaDavydkin Valerij Jur'EvichAleshkin Vladimir AndrianovichDavydkin Igor' Jur'Evich

(73)

Holder

Federal'Noe Gosudarstvennoe Uchrezhdenie Nauki Nauchno-Issledovatel'Skij Institut Ehpidemiologii I Mikrobiologii Imeni G.N. Gabrichevskogo Federal'Noj Sluzhby Po Nadzoru V Sfere Zashchity Prav Potrebitelej I Blagopoluchija Cheloveka" Mniiehm Im. G.N. Gabrichevskogo Rospotrebnadzora)

METHOD OF OBTAINING IMMUNOGLOBULIN MEDICINE Russian patent published in 2009 - IPC A61K39/395 C07K16/06

Abstract RU 2371200 C1

FIELD: medicine.

SUBSTANCE: invention concerns medicine and biotechnology, and method of obtaining immunoglobulin medicines. Method of obtaining immunoglobulin medicines involves a sequential processing of alcohol sediment B (Cohn III fraction) by tenfold volume of 0.9% sodium chloride solution and by chloroform in 0.1%-3.0% end concentration, centrifugation, addition of copper sulfate to centrifugate at pH 6-8, sediment removal by centrifugation, and further extraction of target product by ultrafiltration method in the presence of complex-forming compounds, product stabilisation, clearing and stabilising filtration. Copper sulfate is taken in 0.003-0.03% concentration.

EFFECT: increased content of separated immunoglobulin A fraction, improved product quality.

3 ex

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RU 2 371 200 C1

Authors

Melikhova Aleksandra Vadimovna

Davydkin Valerij Jur'Evich

Aleshkin Vladimir Andrianovich

Davydkin Igor' Jur'Evich

Dates

2009-10-27—Published

2008-06-03—Filed