FIELD: chemistry.
SUBSTANCE: invention relates to an improved highly-selective method of producing deserpidine (Ia) through demethylation of 11-methoxy group of 11-O-methyl reserpic acid lactone, with subsequent stages for reduction, hydrolysis and esterification of the obtained methyldeserpidate 3,4,5-trimethoxybenzoic acid. Output is 40%.
EFFECT: method for semisynthesis of deserpidine is described.
6 cl, 7 ex
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