ALPHA-CRYSTALLINE FORM OF SUBSTITUTED SELENOXANTHENES AND METHOD OF PRODUCING SAID FORM Russian patent published in 2009 - IPC C07D345/00 A61K31/95 A61P3/06 A61P37/00 A61P9/10 

Abstract RU 2374238 C1

FIELD: chemistry.

SUBSTANCE: invention relates to organic chemistry, particularly to the technology of producing selenoxanthenes and can be used in producing food additives, medicinal agents and cosmetic agents, which exhibit broad biological activity. An agent is described, which is an α-crystalline form of 9-phenyl-sym-octahydroselenoxanthene, which has antixodant, detoxication, immunomodulating, antiatherogenic, antisclerotic, anabolic, hypolipid action, and the corresponding structural formula with powder X-ray pattern obtained on Cu-K radiation sources with characteristic reflection indices expressed in degrees of the diffraction angle 2θ: 6.0 12.0 15.0 17.0 19.0 20.0 21.5, 21.7, 20.9 25.0 27.0 28.0 29.0 37.0 and melting temperature 96.8°C, as well as to a method of producing said agent, involving crystallisation of the corresponding 9-R-sym-hydroselenoxanthene from low-polar or non-polar solvent, preferably hexane, chloroform or isopropyl alcohol.

EFFECT: design of an efficient method of producing selenoxanthenes.

3 cl, 1 dwg, 1 tbl

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RU 2 374 238 C1

Authors

Roziev Rakhimdzhan Akhmetdzhanovich

Tsyb Anatolij Fedorovich

Goncharova Anna Jakovlevna

Khomichenok Viktor Vladimirovich

Podgorodnichenko Vladimir Konstantinovich

Dates

2009-11-27Published

2008-03-18Filed