NITROOXY-DERIVATIVES OF LOSARTAN, VALSARTAN, CANDESARTAN, TELMISARTAN EPROSARTAN AND OLMESARTAN AS BLOCKERS OF ANGIOTENSIN II RECEPTORS FOR TREATING CARDIOVASCULAR DISEASES Russian patent published in 2009 - IPC C07D403/10 A61K31/4178 A61K31/4184 A61P9/10 

Abstract RU 2374240 C2

FIELD: chemistry.

SUBSTANCE: present invention relates to new nitro-derivatives of blockers of angiotensin II receptors of formula R-(Y-ONO2)s (I), (values of radicals R, Y and s are given in the formula of invention) with broad pharmacological effect and high transferability.

EFFECT: obtaining compounds which can be used for treating cardiovascular diseases, kidney diseases, chronic liver diseases and inflammatory processes.

6 cl, 6 tbl, 22 ex

Similar patents RU2374240C2

Title Year Author Number
TETRAZOLE DERIVATIVES 1992
  • Pol Ehduord Oldrich[Us]
  • Dzhon Dzhonehs Vytotehs Dankaja[Us]
  • Majkl Ehrnst Piehrs[Us]
RU2091376C1
NEW IMIDAZOLE-5-CARBOXYLIC ACID ACYLALES, METHOD OF PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION HAVING PROPERTIES OF RECEPTOR ANGIOTENSINE II ANTAGONIST 1992
  • Diter Binder[At]
  • Jozef Vajnberger[At]
RU2105764C1
TETRASUBSTITUTED DERIVATIVES OF IMIDAZOLE, METHODS OF THEIR SYNTHESIS, INTERMEDIATE COMPOUNDS AND PHARMACEUTICAL COMPOSITION 1995
  • Alan Korb'E
  • P'Er Depre
  • Mishel' Fortehn
  • Zhak Gijom
  • Bertran Ehkman
RU2174513C2
DERIVATIVES OF PROPIONIC ACIDS AND THEIR USING AS hPPARs ACTIVATORS 2003
  • Besuik Pol Dzhon
  • Kharling Dzhon Dejvid
  • Klintkhaus Savvas
  • Pejtel Vajpalk'Jumar Kantibkhaj
  • Simpson Dzhul'Et
  • Lambert Millard Kherst Iii
RU2316539C2
DUAL-ACTING ANTIHYPERTENSIVE COMPOUNDS, METHODS FOR PREPARING THEM, BASED PHARMACEUTICAL COMPOSITIONS AND INTERMEDIATE COMPOUNDS 2008
  • Allegretti Pol
  • Choi Seok-Ki
  • Gendron Roland
  • Fazeri Pol R.
  • Dzhendza Kit
  • Makkinnell Robert Mjurrej
  • Makmertri Darren
  • Olson Bruk
RU2476427C2
IMIDAZOLE DERIVATIVES 1992
  • Dehvid Dzhon Karini[Us]
  • Dzhon Dzhonas Vitautas Dansia[Us]
  • Pankras Chor Bun Vong[Us]
RU2017733C1
IMIDAZOLE DERIVATIVES, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION DECREASING BLOOD PRESSURE 1992
  • Al'Bert Vagner[De]
  • Khajnrikh Ehnglert[De]
  • Khajnts-Verner Kleemann[De]
  • Khermann Gerkhards[De]
  • Bernvard Shel'Kens[De]
  • Rajnkhard Beker[De]
  • Vol'Fgang Lints[De]
RU2104272C1
XIA FACTOR INHIBITORS 2016
  • Xu Jiayi
  • Ali Amjad
  • Zhou Wei
  • Gao Ying-Duo
  • Edmondson Scott D.
  • Mertz Eric
  • Neelamkavil Santhosh F.
  • Liu Weiguo
  • Sun Wanying
  • Shen Dong-Ming
  • Harper Bart
  • Zhu Cheng
  • Bara Thomas
  • Lim Yeon-Hee
  • Yang Meng
RU2728783C2
SUBSTITUTED AZOLES AND A METHOD OF THEIR SYNTHESIS 1991
  • Rajner Khenning[De]
  • Adal'Bert Vagner[De]
  • Khermann Gerkhards[De]
  • Bernvard Shel'Kens[De]
RU2047604C1
IMIDAZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITION 1991
  • Majkl A.Poss[Us]
RU2111208C1

RU 2 374 240 C2

Authors

Almirante Nikoletta

Del' Soldato P'Ero

Ongini Ehnnio

Dates

2009-11-27Published

2004-07-20Filed