METHOD FOR MAKING PROANTHOCYANIDINES OF SCOTCH PINE BARK Russian patent published in 2009 - IPC A61K36/15 C07D311/62 A61P39/06 

Abstract RU 2375070 C1

FIELD: medicine.

SUBSTANCE: invention refers to production of medicinal, veterinary, cosmetic preparations, and also to food industry and agriculture. Ground pine bark is extracted with boiling 10-15% ethanol within 0.5-1.0 hours at water duty 1:10-15. The water-alcohol solution is separated from bark, concentrated to 1/4 of original volume, saturated with sodium chloride with filtering separation of made deposit. Filtrate is three-fold extracted with ethyl acetate, and ethyl acetate solution is vacuum concentrated to 1/5 of original volume. The concentrated ethyl acetate solution is 5-7-fold dissolved with chloroform with recovering proanthocyanidines.

EFFECT: higher yield of proanthocyanidines.

3 ex

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RU 2 375 070 C1

Authors

Levdanskij Vladimir Aleksandrovich

Butylkina Anna Il'Inichna

Levdanskij Aleksandr Vladimirovich

Kuznetsov Boris Nikolaevich

Dates

2009-12-10Published

2008-10-06Filed