ANTICOAGULANT Russian patent published in 2010 - IPC A61K36/185 A61P7/02 

Abstract RU 2399377 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: anticoagulant exhibiting a thrombin and factor Xa inhibiting activity represents a solution of biologically active birch bark complex prepared by water extraction of ground birch bark on boiling, concentration of aqueous extract and sodium chloride saturation, sediment discharge, ethyl acetate extraction of filtrate, concentration of filtrate, dilution with chloroform, sediment filtration and dissolution to ensure final concentration of 1.0-251.2 mcg/ml, effective for thrombin activity inhibition, and final concentration of 0.1-851.0 mcg/ml, effective for blood coagulation factor Xa activity inhibition.

EFFECT: invention allows implementing thrombin activity inhibition.

3 ex, 2 tbl

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RU 2 399 377 C1

Authors

Kuznetsova Svetlana Alekseevna

Drozd Natal'Ja Nikolaevna

Kuznetsov Boris Nikolaevich

Makarov Vladimir Aleksandrovich

Levdanskij Vladimir Aleksandrovich

Miftakhova Nadzhija Tairovna

Dates

2010-09-20Published

2009-03-13Filed