FIELD: medicine.
SUBSTANCE: block copolymer is produced by reaction of a compound containing a structure fragment of polyethylene glycol and a structure fragment of polyamino acid in a solvent at temperature 30 to 60°C within 2-48 hours. The prepared block copolymer is used as a carrier for an anticarcinogenic taxtane agent, particularly Paclitaxel in a micellar preparation in amount required for disease treatment.
EFFECT: ensured absence of allergic reaction, higher solubility of the sparingly water-soluble anticarcinogenic agent, maintained high blood concentration of the medicine, accumulation of high concentration of the medicine in tumour tissue, intensified pharmacological action and decrease in by-effects.
13 cl, 6 tbl, 4 ex
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Authors
Dates
2009-12-10—Published
2005-09-16—Filed