DERIVATIVES OF BENZAMIDE, METHOD OF THEIR PRODUCTION AND THEIR APPLICATION, PHARMACEUTICAL COMPOSITION AND METHOD FOR PROVISION OF INHIBITING ACTION IN RESPECT TO HDAC Russian patent published in 2009 - IPC C07D211/14 C07D213/56 C07D215/12 C07D239/26 C07D251/18 C07D277/30 C07D295/14 C07D307/54 C07D401/12 C07D403/04 C07D409/04 C07D473/08 C07D495/04 A61K31/452 A61K31/4425 A61K31/495 A61K31/505 A61P35/00 

Abstract RU 2376287 C2

FIELD: medicine.

SUBSTANCE: invention is related to compound of formula (I), (values of radicals are described in formula of invention) or its pharmaceutically acceptable salts, to methods of its production, pharmaceutical composition, which contains it. Application of invention is described for manufacturing of medicinal agent intended for provision of inhibiting action in respect to HDAC in warm-blooded animal, in production of agent used for treatment of malignant tumor. Method is also described for provision of inhibiting action in warm-blooded animal.

EFFECT: compounds have inhibiting activity in respect to HDAC.

15 cl, 17 tbl, 24 ex

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RU 2 376 287 C2

Authors

Stouks Ehlejn Sofi Ehlizabet

Roberts Krejg Antoni

Uoring Majkl Dzhejms

Dates

2009-12-20Published

2003-04-02Filed