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2 478 632

(13)

(51)

IPC

C07D401/14(2006-01-01)

C07D403/04(2006-01-01)

C07D403/14(2006-01-01)

C07D407/14(2006-01-01)

C07D409/14(2006-01-01)

A61K31/517(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2009103900/04, 2007-07-05

(24)

Start date

2007-07-05

(22)

Actual filing date

2007-07-05

(45)

Published

2013-04-10

(72)

Inventor

Mitchell Jan S.Blehjk Dzhejms F.Ksu RuiKallan Nikolas K.Ksiao DengmingSpenser Kit LiBenksik Jozef R.Liang DzunSafina BrajanChzhang BirongChabot KristinDo StivenUolles Ilaj M.Behnka Anna L.Shlekhter Stiven T.

(73)

Holder

Ehrrehj Biofarma Ink.Dzhenentek, Ink.

HYDROXYLATED AND METHOXYLATED CYCLOPENTA[B]PYRIMIDINES AS PROTEIN KINASE INHIBITORS Russian patent published in 2013 - IPC C07D401/14 C07D403/04 C07D403/14 C07D407/14 C07D409/14 A61K31/517 A61P35/00

Abstract RU 2478632 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to new compounds of general formula (I), (the radical values are presented in the patent claim) including their split enantiomers, split diastereomers, solvates and pharmaceutically acceptable salts. What is also described is a method for preparing new compounds, a pharmaceutical composition containing them.

EFFECT: use of the compounds as protein kinase inhibitors and a method of treating cancer.

113 cl, 49 ex, 1 tbl

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RU 2 478 632 C2

Authors

Mitchell Jan S.

Blehjk Dzhejms F.

Ksu Rui

Kallan Nikolas K.

Ksiao Dengming

Spenser Kit Li

Benksik Jozef R.

Liang Dzun

Safina Brajan

Chzhang Birong

Chabot Kristin

Do Stiven

Uolles Ilaj M.

Behnka Anna L.

Shlekhter Stiven T.

Dates

2013-04-10—Published

2007-07-05—Filed