EMULSION INACTIVATED ASSOCIATED VACCINE AGAINST CATTLE PARAGRIPPE-3, REDNOSE AND CORONOVIRAL INFECTION Russian patent published in 2010 - IPC A61K39/295 C12N7/00 A61P31/12 

FIELD: veterinary science.

SUBSTANCE: invention relates to veterinary virology and biotechnology. The vaccine contains an active substance and a target additive. The vaccine active substance is represented by a mixture of avirulent refined antigen material from the VGNKI-4 strain of cattle paragrippe-3 virus, Paramyxoviridae family, Parainfluenza genus, Parainfluenza virus 3 subtype, collection of Federal State Institution "Russian National Research Institute for Control, Standardisation and Certification of Veterinary Preparations", "VGNI-4 DEP", avirulent refined antigen material from the VNIIZZh strain of cattle rednose virus, Herpesviridae family, Varicellavirus genus, collection of Federal State Institution "Russian National Research Institute for Control, Standardisation and Certification of Veterinary Preparations", "VNIIZZh-DEP", and of avirulent refined antigen material from the VNIIZZh strain of cattle coronavirus, Coronaviridae family, Coronavirus genus, collection of Federal State Institution "Russian National Research Institute for Control, Standardisation and Certification of Veterinary Preparations", "VNIIZZh-DEP". The strains are taken at a ratio of 1: 1: 1 and in quantities ensuring protective immune activity of each antigen in the animal organism after receipt of the target preparation injection.

EFFECT: with the animals having been immunised the vaccine induces a high level of antigens; immunity with them is generated within 10-15 days after the vaccine re-injection and sustains for at least 6 months.

15 cl, 7 tbl, 4 ex