ASSOCIATED INACTIVATED EMULSION BOVINE VIRAL DIARRHOEA, ROTAVIRUS AND CORONAVIRUS INFECTIONS VACCINE Russian patent published in 2014 - IPC A61K39/295 A61K39/15 A61K39/215 C12N7/00 

FIELD: medicine.

SUBSTANCE: invention refers to veterinary virology and biotechnology, and concerns a bovine viral diarrhoea, rotavirus and coronavirus infections vaccine. The described vaccine contains an active substance and a target additive. As the active substance, the vaccine contains a mixture of an avirulent purified antigen material of the strain NADL-VNIIZZh-DEP of bovine viral diarrhoea of the family Flaviviridae, of the genus Pestivirus, an avirulent purified antigen material of the strain 101 VNIIZZh-DEP of bovine rotavirus of the family Reoviridae, of the genus Rotavirus, and an avirulent purified antigen material of the strain VNIIZZh-DEP of bovine coronavirus of the family Coronaviridae, of the genus Coronaivirus deposited in the Russian National Collection of Microorganism Strains used in veterinary science and animal industry. The strains are taken in the relation of 1:1:1 in the amounts to provide the protective immune activity of each antigen in an animal's body after the target preparation is introduced.

EFFECT: vaccine induces a high antibody concentration and provides the expressed and long-lasting immunity in the immunised animals .

31 cl, 9 tbl, 5 ex