INACTIVATED EMULSION ASSOCIATED VACCINE FOR CATTLE PARAINFLUENZA-3, INFECTIOUS RHINOTRACHEITIS AND VIRAL DIARRHOEA Russian patent published in 2014 - IPC A61K39/12 A61K39/15 A61K39/155 A61K39/265 A61K39/295 

FIELD: medicine.

SUBSTANCE: invention refers to veterinary virology and biotechnology. The vaccine contains an active substance and a target additive. As the active substance, the vaccine contains a mixture of an avirulent purified antigen material of the strain VGNKI-4 of PI-3 virus of the family Paramyxoviridae, the genus Parainfluenza, the subtype Parainfluenza virus 3, the collection of VGNKI No. VGNKI-4-DEP, of an avirulent purified antigen material of the strain VNIIZZh of cattle IRT virus of the family Herpesviridae, the genus Varicellavirus, of the collection of VGNKI VNIIZZh-DEP and of an avirulent purified antigen material of the strain NADL-VNIIZZh of cattle VD virus of the family Flaviviridae, of genus Pestivirus, of the collection FGU VGNKI NADL-VNIIZZh- DEP. The strains are taken in the relation of 1:1:1 in the amounts to provide the protective immune activity of each antigen in an animal's body after the target preparation is introduced.

EFFECT: vaccine induces the high antibody level in immunised animals; the immunity in the immunised animals is formed 10-15 days after the repeated introduction of the vaccine and preserved for at least 6 months; when the above antigens are combined, a synergetic effect is observed that enables reducing the quantity of antigens in the preparations with the preserved and continuous immunity.

27 cl, 9 tbl, 4 ex