FIELD: medicine.
SUBSTANCE: there are described recombinant plasmids pL1spCBD and pL2spCBD. There are offered strains Escherichia coli that are producers of chimeric proteins L1spCBD and L2spCBD. There are described recombinant proteins L1spCBD and L2spCBD. There is disclosed method of immobilisation, concentration and purification of proteins L1spCBD and L2spCBD both cellulose and polystyrene carriers.
EFFECT: specific interaction of recombinant proteins L1spCBD and L2spCBD with specific blood serum antibodies recovered from sick and vaccinated patients and the absence of interaction with serums recovered from healthy people and immunised patients.
8 cl, 1 dwg, 6 ex
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