FIELD: medicine.
SUBSTANCE: invention refers to immunology and biotechnology. There is offered method of cleaning bacterial capsular polysaccharide Neisseria meningitidis or Haemophilus influenzae. Polysaccharide is precipitated with using a cationic detergent, gathered, solubilised with pure ethanol or mixed ethanol:water with final concentration of ethanol 50% to 95%, filtered and then precipitated with calcium or sodium salts. There are described versions of the method of preparing the vaccines with using cleaning capsular polysaccharide. There is disclosed the method for solubilisation of capsular polysaccharide.
EFFECT: application of the invention ensures simple and fast method of cleaning capsular polysaccharide that can find application in medicine for preparing the vaccine.
26 cl, 10 dwg, 24 tbl
