FIELD: medicine.
SUBSTANCE: group of inventions discloses aqueous immunogenic compositions, which, after introduction to subject, are able to induce immune response, which is bactericidal in respect to, at least serogroup W135 n. meningitidis and prophylactic against disease caused by H. influenzae of type b containing conjugated capsular saccharide antigen of serogroup W135 and conjugated capsular saccharide antigen H. influenzae of type b (Hib); where said capsule saccharide antigen Hib is conjugated with mutant diphtheria toxin CRM197 or tetanus toxoid and saccharide serogroup W135 conjugated with diphtheria toxoid, as well as method of immunisation against bacterial meningitis, involving introduction of said compositions and use thereof for preparing drugs.
EFFECT: group of inventions provides wide spectrum protection against infection of serogroup B, as well as total activity against meningococcus serogroup W135.
64 cl, 9 tbl
Authors
Dates
2016-08-27—Published
2009-09-10—Filed