METHOD OF PRODUCING 2-ALKYL-5,6,7,8,9,10-HEXAHYDRO-4H-CYCLONONE [b]THIOPHENES Russian patent published in 2010 - IPC C07D333/78 

FIELD: chemistry.

SUBSTANCE: invention relates to a method of producing 2-alkyl-5,6,7,8,9,10-hexahydro-4H-cyclonone[b]thiophenes of general formula : (1), where R=n-C₅H₁₁, n-C₇H₁₅, n-C₉H₁₉, characterised by that the mixture of cyclonone-1,2-diene and alka-1,2-diene (octa-1,2-diene, deca-1,2-diene, dodeca-1,2-diene) is reacted with ethylmagnesium bromide (EtMgBr/ether) in the presence of Mg (powder) and titanocene dichloride (Cp₂TiCl₂) catalyst, taken in molar ratio cyclonone-1,2-diene : alka-1,2-diene : EtMgBr : Mg : Cp₂TiCl₂= 10:10:(22-26):20:(1.0-1.4), preferably 10:10:24:20:1.2, in an argon atomosphere at room temperature (20-22°C) and atmospheric pressure for 6-8 hours and diethyl ether, with subsequent addition of an amount of elementary sulphur S₈ which is equimolar to EtMgBr, benzene as a solvent and heating the reaction mass for 6 hours at temperature of approximately 40°C, then after evaporation of light solvents, the reaction mass is kept for 1 hour at temperature of approximately 140°C.

EFFECT: compounds can be used in the food industry as components of flavour boosters, biologically active compounds, dyes, oil additives and hydraulic liquids.

1 cl, 1 tbl, 1 ex