METHOD OF PRODUCING 1,2,3,4,5,6,7,9,10,11,12,13,14,15-TETRADECAHYDRODICYCLONONE[b,d]THIOPHENE Russian patent published in 2010 - IPC C07D333/78 

FIELD: chemistry.

SUBSTANCE: invention relates to a method of producing 1,2,3,4,5,6,7,9,10,11,12,13,14,15-tetradecahydrodicyclonone[b,d]thiophene of general formula : characterised by that, cyclonone-1,2-diene is reacted with ethylmagnesium bromide (EtMgBr/ether) in the presence of Mg (powder) and titanocene dichloride (Cp₂TiCl₂) catalyst taken in molar ratio cyclonone-1,2-diene : EtMgBr : Mg : Cp₂TiCl₂ = 20:(22-26):20:(1.0-1.4), preferably 20:24:20:1.2, in an argon atmosphere at room temperature (20-22°C) and atmospheric pressure for 6-8 hours in diethyl ether, with subsequent addition of an amount of elementary sulphur S₈ which is equimolar to EtMgBr, benzene as a solvent and heating the reaction mass for 5 hours at temperature of approximately 40°C, then after evaporation of light solvents, the reaction mass is kept for 1 hour at temperature of approximately 140°C.

EFFECT: compounds can be used in fine organic synthesis and in production of biologically active heterocyclic compounds.

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