PHYSICALLY STABLE X-RAY AMORPHOUS FORM OF RANITIDINE HYDROCHLORIDE WITH IMPROVED ANTIULCER ACTIVITY AND METHOD FOR PREPARING THEREOF Russian patent published in 2010 - IPC A61K31/34 

Abstract RU 2385155 C2

FIELD: medicine.

SUBSTANCE: invention refers to medicine and concerns a new, earlier unknown form of ranitidine hydrochloride exhibiting properties of H2-blocker. Invention consists that the form of ranitidine is X-ray amorphous. The X-ray amorphous form is physically stable, there is also described the method for preparing said X-ray amorphous form of earlier known crystal modifications.

EFFECT: invention provides preparing the new X-ray amorphous form of ranitidine hydrochloride exhibiting improved specific antiulcer activity.

12 cl, 1 tbl, 2 dwg

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RU 2 385 155 C2

Authors

Leonidov Nikolaj Borisovich

Uspenskaja Svetlana Igorevna

Krasnokutskij Aleksandr Borisovich

Dates

2010-03-27Published

1998-08-18Filed