MACROCYCLIC POLYMORPHS, COMPOSITIONS CONTAINING SUCH POLYMORPHS, AND METHODS FOR USING AND PREPARING THEM Russian patent published in 2013 - IPC C07H17/08 A61K31/7048 A61P31/04 

Abstract RU 2478643 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to new forms of compounds of formula I possessing broad-spectrum antibiotic activity, especially crystalline polymorphous forms of such compounds, also in the form of a hydrate or a solvate, particularly crystalline polymorph of tiacumicin. The invention also refers to compositions containing such crystalline polymorphous compounds, methods for preparing and using them.

EFFECT: there are presented pharmaceutical compositions possessing antibiotic activity, containing crystalline polymorphs in a therapeutically effective amount and a pharmaceutically acceptable excipient.

26 cl, 5 ex, 4 tbl, 3 dwg

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RU 2 478 643 C2

Authors

Tiu Ju-Khung

Te Tessi Mehri

Romero Aleks

Itikava Esi

Shu Eue-Kong

Dates

2013-04-10Published

2008-01-22Filed