FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to new forms of compounds of formula I possessing broad-spectrum antibiotic activity, especially crystalline polymorphous forms of such compounds, also in the form of a hydrate or a solvate, particularly crystalline polymorph of tiacumicin. The invention also refers to compositions containing such crystalline polymorphous compounds, methods for preparing and using them.
EFFECT: there are presented pharmaceutical compositions possessing antibiotic activity, containing crystalline polymorphs in a therapeutically effective amount and a pharmaceutically acceptable excipient.
26 cl, 5 ex, 4 tbl, 3 dwg
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Authors
Dates
2013-04-10—Published
2008-01-22—Filed