FIELD: medicine.
SUBSTANCE: invention aims at preparation of new strain of hybrid cells Mus. Musculus 6F3 - a producer of monoclonal antibody (MCA) to hemagglutinin protein of high-pathogen avian influenza virus A/duck/Novosibirsk/56/05. Strain 6F3 is prepared by fusing murine myeloma cells Sp2/0 with murine spleen cells BALB/c, immunised with a purified and inactivated preparation of avian influenza virus A/H5N1 (strain A/duck/Novosibirsk/56/05). Hybridoma produced MCA belong to IgA class. Strain 6F3 is deposited in the Collection of cell culture of Ivanovsky State Research Institution of Virology of the Russian Academy of Medical Sciences, No. 8/2/3. Using hybridoma allows producing specific monoclonal antibodies to hemagglutinin protein of avian influenza virus A/H5N1.
EFFECT: possibility to use antibodies to studying the antigenic structure of hemagglutinin for differential diagnostics of avian influenza virus A/H5 serotype.
1 dwg, 6 ex
| Title | Year | Author | Number |
|---|---|---|---|
| STRAIN OF HYBRID CULTIVATED MURINE CELLS Mus Musculus - 4F11 PRODUCING MONOCLONAL ANTIBODY RESPONDER WITH HEMAGGLUTININ PROTEIN OF HIGH-PATHOGEN STRAIN virus A/duck/Novosibirsk/56/05 H5N1 | 2008 |
|
RU2384617C1 |
| STRAIN OF BIRD FLU VIRUS OF A/common gull/Chany/2006 H5N1 SUBTYPE FOR PREPARATION OF ANTIGEN-CONTAINING DIAGNOSTIC OR VACCINE MEDICATION | 2009 |
|
RU2400536C1 |
| CULTIVATED HYBRID CELL STRAIN OF MOUSE Mus. Musculus-1E7 PRODUCER OF MONOCLONAL ANTIBODY IMMUNORESPONSIVE TO HAEMAGGLUTININ PROTEIN OF PANDEMIC INFLUENA VIRUS A/IIV-Moscow/01/09(H1N1)sw1 | 2011 |
|
RU2457243C1 |
| METHOD FOR INITIAL ISOLATION OF INFLUENZA VIRUS A STRAIN, STRAIN VIRUS A/DUCK/NOVOSIBIRSK/56/05 H5N1 FOR PREPARATION FOR DIAGNOSIS, PROPHYLAXIS AND THERAPEUTICAL AGENTS, AND FOR EVALUATION OF ANTIVIRAL ACTIVITY OF VARIOUS COMPOUNDS | 2005 |
|
RU2309983C2 |
| YAMAL STRAIN OF AVIAN INFLUENZA VIRUS OF ALPHAINFLUENZAVIRUS GENUS OF INFLUENZA A VIRUS SUBTYPE H5N1 SPECIES FOR THE MANUFACTURE OF BIOLOGICAL PRODUCTS FOR THE SPECIFIC PREVENTION OF AVIAN INFLUENZA TYPE A SUBTYPE H5 | 2022 |
|
RU2796987C1 |
| AVIAN INFLUENZA STRAIN A/Goose/Krasnoozerskoye/627/05 SUBTYPE H5N1 FOR STUDY OF STRENGTH OF THERAPEUTIC AND PREVENTIVE INFLUENZA AGENTS | 2008 |
|
RU2366709C1 |
| STRAIN A/CHIKEN/KOSTROMA/3175/17 H5N2 OF AVIAN INFLUENZA VIRUS SUBTYPE H5N2 INFUENZA A VIRUS OF GENUS ALPHAINFLUENZAVIRUS TO CONTROL ANTIGENIC AND IMMUNOGENIC ACTIVITY OF AVIAN INFLUENZA VACCINES AND FOR MAKING ANTIGEN-CONTAINING DIAGNOSTICUMS | 2020 |
|
RU2736788C1 |
| INACTIVATED VACCINE AGAINST AVIAN INFLUENZA EMULSIFIFIED BY FLU PROTECT H5 AND METHOD OF AVIAN INFLUENZA PREVENTION | 2007 |
|
RU2350350C1 |
| STRAIN OF INFLUENZA VIRUS A/COMMON MUSKRAT/CHANY LAKE/226/05 H2N2-SUBTYPE FOR USE IN DIAGNOSTICS OF INFLUENZA VIRUS BY METHODS OF RTGA AND PCR AND STUDYING EFFICACY OF ANTIVIRAL PREPARATIONS IN VITRO AND IN VIVO | 2015 |
|
RU2606030C1 |
| STRAIN OF INFLUENZA VIRUS A/BLACK-HEADED GULL/KAMCHATKA/123/2013 H11N8-SUBTITLE FOR USE IN INFLUENZA VIRUS DIAGNOSIS BY HIR AND PCR METHODS AND STUDY OF EFFECTIVENESS OF IN VITRO AND IN VIVO ANTI-VIRAL PREPARATIONS | 2016 |
|
RU2631932C1 |
