YAMAL STRAIN OF AVIAN INFLUENZA VIRUS OF ALPHAINFLUENZAVIRUS GENUS OF INFLUENZA A VIRUS SUBTYPE H5N1 SPECIES FOR THE MANUFACTURE OF BIOLOGICAL PRODUCTS FOR THE SPECIFIC PREVENTION OF AVIAN INFLUENZA TYPE A SUBTYPE H5 Russian patent published in 2023 - IPC C12N7/00 

Abstract RU 2796987 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to a new strain of influenza virus type A subtype H5 fam. Orthomyxoviridae of Alphainfluenzavirus genus deposited in the All-Russian State Collection of Exotic Types of FMD Viruses and Other Animal Pathogens (GKSHM) of the Federal State Budgetary Institution "ARRIAH" under registration number: No. 366-dep/20-28-GKSHM of the FSBI "ARRIAH". The proposed strain is reproduced in 9-11-day-old chicken embryos SPF chickens, where it reaches an infectious titer of at least 8.2 lg EID50/cm3. As part of an inactivated vaccine, the strain has pronounced antigenic and immunogenic properties, causing the production of specific antibodies captured in RTHA.

EFFECT: strain presented can be used for the manufacture of biological products for the specific prevention of avian influenza type A subtype H5.

1 cl, 1 dwg, 7 tbl, 8 ex

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RU 2 796 987 C1

Authors

Moroz Natalya Vladimirovna

Frolov Sergej Vladimirovich

Zhestkov Pavel Dmitrievich

Andrejchuk Dmitrij Borisovich

Chvala Ilya Aleksandrovich

Ruchnova Olga Ivanovna

Dates

2023-05-30Published

2022-08-03Filed