METHOD FOR PREPARING BETULIN NANOSUSPENSION AND/OR ITS DERIVATIVES Russian patent published in 2010 - IPC A61K36/185 A61K31/15 

Abstract RU 2386446 C1

FIELD: medicine.

SUBSTANCE: invention concerns applied biotechnology, particularly the method for preparing betulin nanosuspension and/or its derivatives. The method for preparing betulin nanosuspension and/or its derivatives by combination of betulin solution and/or its derivatives in an organic solvent with edible oil or an aqueous solution of surface-active substance in an actuator of a colloid mill in intensive stirring and homogenisation within circulation under the certain conditions, with following vacuum-assisted removal of the remained solvent.

EFFECT: method allows producing stable betulin nanosuspension and/or its derivatives with the improved permeability through capillary walls and cell membranes and greater expressiveness of biological effect in comparison with common analogues.

5 cl, 12 ex

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RU 2 386 446 C1

Authors

Sternin Jurij Igorevich

Jurchenko Igor' Vasil'Evich

Moskalev Evgenij Vladimirovich

D'Jachuk Georgij Ivanovich

Evsjukov Aleksandr Igorevich

Dates

2010-04-20Published

2008-12-01Filed