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IPC

C07D209/42(2006-01-01)

A61K31/404(2006-01-01)

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Application

2008115405/04, 2008-04-23

(24)

Start date

2008-04-23

(22)

Actual filing date

2008-04-23

(45)

Published

2010-04-20

(72)

Inventor

Verkhovskij Jurij Grigor'EvichTsyshkova Nina GavrilovnaTrofimov Fedor AleksandrovichRoziev Rakhimdzhan AkhmetdzhanovichTsyb Anatolij FedorovichGoncharova Anna JakovlevnaPodgorodnichenko Vladimir Konstantinovich

(73)

Holder

Obshchestvo S Ogranichennoj Otvetstvennost'Ju

DERIVATIVES OF 5-HYDROXY-4-AMINOMETHYL-1-CYCLOHEXYL (OR CYCLOHEPTYL)-3-ALKOXYCARBONYLINDOLES, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, HAVING ANTIVIRAL ACTIVITY AND METHOD OF PRODUCING SAID COMPOUNDS Russian patent published in 2010 - IPC C07D209/42 A61K31/404

Abstract RU 2386616 C2

FIELD: chemistry.

SUBSTANCE: invention relates to an agent which has antiviral activity towards influenza A virus, which is a derivative of 5-hydroxy-4-aminomethyl-1-cyclohexyl (or cycloheptyl)-3-alkoxycarbonylindoles of general formula (I) , where X denotes - H; n=1, 2; R₃ denotes C₁-C₅alkyl; Alk denotes C₁-C₆alkyl; R₁ and R₂ are independently selected from C₁-C₄-alkyl, mainly CH₃, or its pharmaceutically acceptable salts.

EFFECT: obtaining an agent which has antiviral activity towards influenza A virus.

2 dwg, 2 tbl, 3 ex

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RU 2 386 616 C2

Authors

Verkhovskij Jurij Grigor'Evich

Tsyshkova Nina Gavrilovna

Trofimov Fedor Aleksandrovich

Roziev Rakhimdzhan Akhmetdzhanovich

Tsyb Anatolij Fedorovich

Goncharova Anna Jakovlevna

Podgorodnichenko Vladimir Konstantinovich

Dates

2010-04-20—Published

2008-04-23—Filed