SALTS AND POLYMORPHS OF 8-FLUORO-2-{4-[(METHYLAMINO)METHYL]PHENYL}-1,3,4,5-TETRAHYDRO-6H-AZEPINO[5,4,3-cd]INDOL-6-ONE Russian patent published in 2015 - IPC C07D487/06 A61K31/55 A61P35/00 

Abstract RU 2570198 C2

FIELD: chemistry.

SUBSTANCE: invention relates to camsilate and maleate salts of 8-fluoro-2-{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one and to a pharmaceutical composition having activity which is mediated by poly(ADP-ribose)polymerase (PARP), which contains a therapeutically effective amount of the disclosed salt.

EFFECT: obtaining camsilate and maleate salts of 8-fluoro-2-{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one, having high hydration resistance.

15 cl, 38 dwg, 31 tbl, 31 ex

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RU 2 570 198 C2

Authors

Patrishija Ehnn Basford

Antoni Majkl Kampeta

Adam Dzhillmor

Matt'Ju Kameron Dzhons

Ehlefterois Kougoulos

Suman Lutra

Robert Uolton

Dates

2015-12-10Published

2011-02-10Filed