FIELD: chemistry.
SUBSTANCE: invention relates to organic chemistry and specifically to crystalline form of maleate 1-((2R,4R)-2-(1H-benzo[d]imidazol-2-yl)-1-methylpiperidin-4-yl)-3-(4-cyano-phenyl)urea, which has X-ray powder diffraction pattern including peaks at 2θ: 11.6, 12.1 and 19.6 °2θ ± 0.2 °2θ. Also described is a pharmaceutical composition based on the crystalline form of said urea maleate.
EFFECT: technical result is obtaining urea maleate, which has improved chemical and thermal stability during storage, low hygroscopicity while maintaining chemical and enantiomeric stability.
12 cl, 7 ex, 8 tbl, 5 dwg
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