FIELD: medicine.
SUBSTANCE: invention relates to chemical-pharmaceutical industry and concerns an inhalation composition containing SAE-β-CD and a corticosteroid. The composition is adapted to sprayed administration with the help of a dispenser. The composition can be provided in a set. The composition is administered in the form of water solution, however, it can be stored as dry power, ready-to-use solution or concentrated composition. The composition is applied with the help of an advanced spray system for corticosteroid inhaled administration. SAE-β-CD contrained in the composition significantly enhances budesonide chemical stability. Invention also concerns method for inhaled administration of the composition. The composition can also be administered nasally with the help of an ordinary device for preparation nasal administration.
EFFECT: composition is characterised with high stability and bioavailability.
37 cl, 20 ex, 18 dwg
Authors
Dates
2010-05-10—Published
2004-12-31—Filed