METHOD OF FORECASTING OF RECURRENT COURSE OF LARYNGOTRACHEITIS IN CHILDREN Russian patent published in 2010 - IPC G01N33/53 G01N33/48 

FIELD: medicine.

SUBSTANCE: initially anamnestic data and clinical features of laryngotracheitis are specified, microbiological and virological studies are conducted in a smear from posterior pharyngeal wall, level of cytokines is determined (interleukine-4, interleukine-6, interferon-α, interferon-γ) and general IgE in peripheral blood, and at presence in a child the following symptoms: allergic pathology in case history, effuse of Streptococcus agalacticae, viral-viral and bacterial-bacterial associations, development of croup syndrome up to 2 stage, reducing of red blood cell level <2.9*10 billion/l and hemoglobin <89 g/l in clinical blood analysis, as well as determining the level of cytokines in peripheral blood: interleukine-4 is higher than 14.8 ng/ml, interleukine-6 is higher than 16.1 ng/ml, interferon-α is higher than 147.8 ng/ml, interferon-γ is lower than 16.9 ng/ml; the level of total IgE in the serum is higher than 47.0, relapsing course is predicted. Using the method enables to determine characteristics of the course of laryngotracheitis in children at an early stage, to take adequate programs of anti-recidivating treatment and conduct targeted immunotherapy.

EFFECT: reduction in frequency of laryngotracheitis recuring in children.

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