ACID ADDITION SALTS OF 5-AMINOLEVULINIC ACID AND ITS DERIVATIVES Russian patent published in 2010 - IPC C07C229/22 C07C227/14 A61K31/195 A61P43/00 

FIELD: chemistry.

SUBSTANCE: invention refers to acid addition salts of 5-amonilevulinic acid ester (5-ALA ester) with acid in the form of solphonic acid derivative selected out of C₁-C₄-alkanesulphonic acid, benzolsulpnonic acid substituted with C_1-4-alkyl, 2-hydroxy-ethanesulphonic acid and (+)-camphor-10-sulphonic acid, or nitric acid, where 5-ALA ester is a compound of the formula R² ₂N-CH₂COCH₂-CH₂CO-OR¹ (R¹ is unramified or ramified C_1-6-alkyl group which can be possibly interrupted with one or two -O- groups and possibly substituted with phenyl, which in turn can be substituted with unramified or ramified C_1-6-alkyl group; R² is hydrogen atom). Also invention refers to methods of obtainment of the claimed salts, their application, pharmaceutical composition and methods of photochemotherapeutical treatment and in vitro diagnostics.

EFFECT: application of claimed salts as photosensitising agents in photodynamic therapy or diagnostics.

23 cl, 2 tbl, 10 dwg, 42 ex