FIELD: medicine, pharmaceutics.
SUBSTANCE: present invention refers to an oral pharmaceutical composition taken between meals for phosphorous compounds absorption from the intestinal liquids, especially from saliva. The composition contains a phosphorus binding agent, and a pharmaceutically acceptable carrier and/or an excipient. The composition is kept in a mouth to exhaust the phosphorus binding agent. The phosphorus binding agent represents a phosphate binding agent polymer, a pharmaceutically acceptable lanthanum salt, a pharmaceutically acceptable magnesium salt, a pharmaceutically acceptable calcium salt, a pharmaceutically acceptable anion-exchange resin, a pharmaceutically acceptable phosphate binding polysaccharide. Preferentially, the agent represents phosphate binding chitosan. The composition is used for treating hyperphosphatemia.
EFFECT: invention provides effective treatment of high blood serum phosphorus concentration and reduces risk of cardiovascular complications in patients.
19 cl, 2 tbl, 2 ex
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Authors
Dates
2010-06-27—Published
2005-11-29—Filed