METHOD FOR ASSESSMENT OF VASCULAR WALL ADAPTATION TO FUNCTIONAL LOAD Russian patent published in 2010 - IPC G01N33/52 G01N33/53 

FIELD: medicine.

SUBSTANCE: before and after local ischemia, diametre of the brachial artery, blood nitrite level, endothelin concentration and Willebrand factor are evaluated. The accommodation of vascular wall endotheliocytes to ischemia is calculated by formula that describes a coefficient K_en. If K_en is "0" or less, the adaptation of the vascular wall is considered as preserved; K_en within "0" to 0.2 inclusive shows the moderately lowered adaptation of the vascular wall, while the K_en value exceeding 0.2 indicates the considerably lowered adaptation of the vascular wall. The coefficient K_en may be used for a quantitative estimation of specific features of cell functional adaptation to ischemic factors, both in norm, and in cardiovascular pathology.

EFFECT: use of the invention allows reducing the acquisition time in 3 times, objectively assessing the endothelium adaptation to ischemia.

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