MEDICAL EMULSION OF PERFLUORORGANIC COMPOUNDS, METHOD OF PREPARATION AND METHOD OF APPLICATION Russian patent published in 2010 - IPC A61K31/02 A61K9/107 B01F3/08 A61P7/08 A61P9/10 

Abstract RU 2393849 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: declared invention refers to chemical-pharmaceutical industry, and concerns an emulsion of perfluororganic compounds (PFOC) for medicine and biology, containing mixed perfluorocarbons (PFC) with a main ingredient being perfluorodecahydronaphthalene (PFD) and mixed perfluorochemical tertiary amines (PFTA) with a main ingredient being perfluoro-N-(4-methylcyclohexyl)-piperidine (PFMCP), having smaller excretion rates than PFD, a stabilising agent and a physiologically acceptable water-salt solution with energy metabolism substrata, differing that all the ingredients of PFOS have critical hexane solution temperatures (TcrH), differing no more than by 2-4°C, and the stabilising agent represents mixed block copolymers from the group of block copolymers polyoxyethylene-polyoxypropylene with an average weight content of polyoxypropylene 20%. The invention also concerns a method for making said emulsion, and a method of treating with applying the declared emulsion.

EFFECT: prepared emulsions show high stability and are non-toxic.

21 cl, 5 tbl, 17 ex, 2 dwg

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RU 2 393 849 C2

Authors

Maevskij Evgenij Il'Ich

Ivanitskij Genrikh Romanovich

Makarov Kirill Nikolaevich

Gervits Lev L'Vovich

Moroz Viktor Vasil'Evich

Dates

2010-07-10Published

2006-12-28Filed