FIELD: medicine.
SUBSTANCE: invention relates to method of adsorbing active agents, in particular proteins or peptides, on the surface of crystal diketopiperazine microparticles, which includes stages of obtaining water suspension of diketopiperazine microparticles and active agent, change of superficial properties of microparticle by changing conditions of suspending, for instance changing solution pH or polarity.
EFFECT: adsorbing of active agent on microparticle takes place independently on stage of solvent removal.
26 cl, 17 dwg, 4 tbl, 7 ex
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