METHOD OF PREVENTING PURULENT COMPLICATIONS OF POST-OPERATIONAL WOUNDS AND TREATMENT OF INFECTED POST-OPERATIONAL WOUNDS WITHOUT SUPPURATION Russian patent published in 2010 - IPC A61M1/38 A61K31/7042 A61K38/19 A61P37/00 A61P41/00 

Abstract RU 2394602 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, in particular to surgery, and can be applied for prevention of purulent complications of post-operational wounds and for treatment of infected post-operational wounds without festering. Method includes carrying out antibiotic therapy and immunotherapy. For immunotherapy blood sampling in patient is carried out, its cell part is separated. Erythrocytic mass is returned to patient. Remaining cell mass is cultured with 500000 IU of interleukin-2 for 60 minutes at temperature 37°C, with following centrifugation and separation of 60-80 ml of supernatant fluid. This fluid, which contains cytokines, is introduced subcutaneously symmetrically at the distance 1.5 cm from borders of post-operational wound until creation of infiltration bank in terms of 10 ml of solution per each 5 cm of wound length from each side. Such introduction is performed on 1, 3 and 5 day of post-operation period.

EFFECT: method increases efficiency of prevention of suppuration in treatment of infected post-operational wound due to creation of high concentration of preparation around wound with enhance of non-specific immune response and healing of wound by primary intention.

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RU 2 394 602 C1

Authors

Konovalov Andrej Aleksandrovich

Alekseev Andrej Mikhajlovich

Churljaev Jurij Alekseevich

Baranov Andrej Igorevich

Luchshev Dmitrij Vladimirovich

Ermolaev Jurij Dmitrievich

Dates

2010-07-20Published

2009-04-07Filed