FIELD: medicine.
SUBSTANCE: registration of fluorescence in vivo and noninvasive is conducted with method of diffusion fluorescence tomography using device where radiation source and radiation detector are located in configuration "peek-a-boo". Analysis of fluorescence intensity is conducted with images of an animal in the frontal plane. Fluorescence registration is conducted both in abdominal cavity organs and in tense areas of skin and abdominal region as a whole. Armpits skin is used as tense areas of skin.
EFFECT: method enables to carry out studies in vivo and non-invasively, to assess accumulation of photosensitiser in skin to select a photosensitiser with minimal skin phototoxicity, enables to assess accumulation of photosensitiser in tissues without using identification of organs while studying dynamics of accumulation and excretion of photosensitisers.
5 ex, 8 dwg
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