CHEMOKINE RECEPTOR ANTAGONISTS Russian patent published in 2010 - IPC C07D401/14 C07D403/14 C07D407/12 C07D407/14 C07D409/14 C07D411/14 C07D413/14 C07D451/06 C07D455/02 C07D498/04 A61K31/405 A61K31/343 A61K31/4468 A61K31/38 A61P31/12 A61P31/18 

Abstract RU 2395506 C2

FIELD: chemistry.

SUBSTANCE: invention describes a compound of formula I or its pharmaceutically acceptable salt , where R, R9, Z, X, Q and Y are defined in the formula of invention. The compounds are chemokine receptor 2 and chemokine receptor 5 antagonists and can be used as a medicinal agent for preventing, relieving or treating autoimmune or inflammatory diseases or conditions.

EFFECT: obtaining a formula (I) compound, a pharmaceutical composition based on the formula (I) compound, use of the compound in paragraph 1 to prepare a medicinal agent for treating an autoimmune or inflammatory disease or condition, as well as use of the compound in paragraph 1 to prepare a medicinal agent for treating HIV infection or AIDS.

11 cl, 181 ex

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RU 2 395 506 C2

Authors

Ehrsperzhe Rene

Janzer Filipp

Pfenninger Ehmil'

Vjutrikh Khans Jurg

Mil'Tts Vol'Fgang

Dates

2010-07-27Published

2005-02-10Filed