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(19)

RU

(11)

2 503 676

(13)

C2

(51)

IPC

C07D487/04(2006-01-01)

C07D471/04(2006-01-01)

C07D519/00(2006-01-01)

A61K31/5025(2006-01-01)

A61K31/437(2006-01-01)

A61P29/00(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2010139566/04, 2009-02-16

(24)

Start date

2009-02-16

(22)

Actual filing date

2009-02-16

(45)

Published

2014-01-10

(72)

Inventor

Bamberg Dzhoj TimotiBartlett MarkDju-Bua Dejzi DzhojEhlvorti Todd RichardKhendriks Robert TanGermann Iogannes KorneliusKondru Rama K.Lemuan RemiLu Jan'Ouehns Timoti D.Park DzhaekhenSmit Dejvid BernardSot MajklJan Khan'BjaoE Kalvin Uehsli

(73)

Holder

F.Khoffmann-Lja Rosh Ag

PYRROLOPYRAZINE KINASE INHIBITORS Russian patent published in 2014 - IPC C07D487/04 C07D471/04 C07D519/00 A61K31/5025 A61K31/437 A61P29/00 A61P35/00 

Abstract RU 2503676 C2

FIELD: chemistry.

SUBSTANCE: invention relates to use of novel pyrrolopyrazine derivatives of formula , where variables Q and R are as defined in the claim, which inhibit JAK and SYK.

EFFECT: high effectiveness when treating autoimmune and inflammatory diseases.

11 cl, 59 ex

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RU 2 503 676 C2

Authors

Bamberg Dzhoj Timoti

Bartlett Mark

Dju-Bua Dejzi Dzhoj

Ehlvorti Todd Richard

Khendriks Robert Tan

Germann Iogannes Kornelius

Kondru Rama K.

Lemuan Remi

Lu Jan'

Ouehns Timoti D.

Park Dzhaekhen

Smit Dejvid Bernard

Sot Majkl

Jan Khan'Bjao

E Kalvin Uehsli

Dates

2014-01-10—Published

2009-02-16—Filed

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