MARKED VIRUS-VACCINE AGAINST AUJESZKY'S DISEASE Russian patent published in 2004 - IPC

Abstract RU 2242247 C2

FIELD: veterinary virology, biotechnology.

SUBSTANCE: invention proposes vaccine comprising virus-containing material from the glycoprotein gE-deleted strain "VK" of Aujeszky's disease virus and protecting medium taken in the effective ratios. The strain is deposited in collection of microorganisms VGNKI at the registration name "VK"-DEP. Virus is reproduced in transplantable culture of cells (VNK-21, PSGK-20, PPK-666 and Ch-91) with the biological activity at least 6.0 lg TCD50/cm3. For preparing the protecting medium 50% sucrose solution, 10% gelatin solution and 20% lactoalbumin hydrolyzate solution are used that are mixed in the ratio = 1.0:0.5:2.5, respectively. Vaccine provides the safety protection against infection pathogen distributing in Russian Federation area.

EFFECT: valuable properties of vaccine.

12 cl, 1 tbl, 11 ex

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RU 2 242 247 C2

Authors

Gusev A.A.

Diev V.I.

Zakharov V.M.

Konstantinov A.V.

Morenkov O.S.

Ulasov V.I.

Blotova G.A.

Mikhalishin V.V.

Dates

2004-12-20Published

2003-01-05Filed