AQUEOUS OPHTHALMIC SUSPENSION OF CRYSTAL REBAMIPIDE Russian patent published in 2010 - IPC A61K31/4704 A61K9/08 A61K9/10 A61K47/32 A61K47/34 A61K47/38 A61P27/02 

Abstract RU 2398585 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to medicine, particularly to an ophthalmic product containing rebamipide characterised by sufficient transparency for tolerant sensations when applied, and a neutral to slightly acidic pH. An aqueous ophthalmic suspension of crystal rebamipide which has the improved transparency is prepared by adding aqueous rebamipide dissolved in a base, such as sodium hydroxide, or aqueous rebamipide salt in aqueous acid solution, such as hydrochloric acid, containing at least one of the compounds chosen from water-soluble polymers or surface-active substances, and by mixing said solutions.

EFFECT: invention allows not to damage keratoconjunctiva of the patient suffering from eye dryness.

12 cl, 9 tbl, 4 dwg, 16 ex

Similar patents RU2398585C2

Title Year Author Number
PHARMACEUTICAL COMPOSITIONS 2009
  • Sumida Sun-Itiro
  • Isikava Siniti
RU2538694C2
AQUEOUS PHARMACEUTICAL SUSPENSION CONTAINING REBAMIPIDE, AND METHOD FOR PREPARING IT 2007
  • Masuda Josito
RU2467751C2
METHODS OF OBTAINING ARIPIPRAZOLE SUSPENSION AND LYOPHILYSED COMPOSITION 2008
  • Khiraoka Shogo
  • Matsuda Takakuni
  • Khatanaka Junichi
RU2483711C2
METHOD OF PREPARING AN AQUEOUS SUSPENSION AND AN AQUEOUS OPHTHALMIC PREPARATION 1992
  • Khisajuki Nakajama[Jp]
  • Kazumiti Usio[Jp]
  • Katsukhiro Inada[Jp]
RU2098094C1
EDARAVONE SUSPENSION FOR ORAL ADMINISTRATION 2019
  • Hayama, Tetsuo
  • Takahashi, Tomohiro
  • Omura, Tomoyuki
  • Hayashi, Kouji
  • Matsuda, Munetomo
  • Miyazawa, Tadashi
RU2810789C2
CATALYST SUBSTRATE OF ALUMINIUM OXIDE 2011
  • Polli Ehndrju
  • Frensis Frensis
  • Inglish Tomas
  • Otake Naotaka
  • Larsh Oliv'E
RU2566748C2
ORAL PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF "DRY EYE" SYNDROME CONTAINING REBAMIPID OR ITS PRECURSOR 2014
  • Cho Eul-Hwan
  • Choi Sung Ju
  • Lee Sung Woo
  • Shin Hee Jong
  • Yoon Jong Bae
  • Park Ki Seok
  • Nam Ho Tae
RU2632107C2
AGENT FOR TREATING TUMOUR AND KIT CONTAINING LIPOSOMAL COMPOSITION OF GEMCITABINE 2016
  • Kitahashi, Tsukasa
  • Mima, Shinji
  • Matsumoto, Takeshi
  • Sekiguchi, Takahiro
  • Mori, Mikinaga
RU2768178C2
PHARMACEUTICAL COMPOSITION OF CARBOXAMIDE INHIBITORS OF HIV INTEGRASE, CONTAINING COMPOSITION WITH CONTROLLED RATE OF RELEASE 2005
  • Purkavoos Nazaneen
  • Nej Dzhejms R.
  • Krjuehjns Marija T.
  • Vu Jun'Khuehj
  • Palkar Saurabkh A.
RU2382648C2
IRINOTECAN LIPOSOMES OR ITS SALTS, METHOD FOR PREPARING THEM 2009
  • Tun Sin'Jun
  • Lehj Gofehn
  • Juj Chehnsja
  • Chehn' Ljan
RU2526114C2

RU 2 398 585 C2

Authors

Matsuda Takakuni

Khiraoka Sogo

Tomokhira Juso

Isikava Siniti

Dates

2010-09-10Published

2005-11-11Filed